This is a typical rectilinear American street corner - two streets pass straight through at 90 degree angles. Notice, though, that even with this simple arrangement, the buildings on the corners are more prominent than any other.
I have not been able to identify where this intersection is, despite good familiarity with San Francisco. It is most likely in one of the flat sections near the Embarcadero and Market Street that were almost entirely destroyed in the 1906 earthquake, so they would have been rebuilt completely not very long after this photograph was taken.
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